What's UpNext
What’s UpNext: Signals from the Global Startup Circuit
The F1 Circuit of the Startup Ecosystem. Tracking founders, momentum, and signals as they emerge.
What’s UpNext: Signals from the Global Startup Circuit
The F1 Circuit of the Startup Ecosystem. Tracking founders, momentum, and signals as they emerge.
Nobody Was Reading the Data Underground. Until Now.
Large multinational clients of LiORA can carry up to $64 billion in AROs, roughly half of which is tied to soil and groundwater contamination. Nick Gray left B2B tech to join LiORA, replacing grab samples with live AI-powered data that finally makes site closure possible.
What’s UpNext: Signals from the Global Startup Circuit
The F1 Circuit of the Startup Ecosystem. Tracking founders, momentum, and signals as they emerge.
Google for Startups Accelerator Canada 2026
Canada's AI ecosystem has moved from research credibility to deployment infrastructure. The 2026 Google Accelerator cohort signals the shift — 14 startups building for enterprise buyers, not labs, with technical stacks vetted for scale.
Building the Hormone-Free Contraceptive Her Patients Couldn’t Find
The possible link between long-term use of hormonal contraception and autoimmune disease led Jennifer Johnston to build a better option for patients. Elle MD’s copper vaginal ring is a once-monthly, hormone-free contraceptive that women can use themselves, without surgery or a prescription routine.
What’s UpNext: Signals from the Global Startup Circuit
The F1 Circuit of the Startup Ecosystem. Tracking founders, momentum, and signals as they emerge.
Web Summit Vancouver 2026: Enterprise AI Deployment Recap
Enterprise AI projects stalled as buyers demanded working systems. Clean tech competed on economics, not ESG. Vancouver surfaced constraint-driven founders.
What’s UpNext: Signals from the Global Startup Circuit
The F1 Circuit of the Startup Ecosystem. Tracking founders, momentum, and signals as they emerge.
What’s UpNext: Signals from the Global Startup Circuit
The F1 Circuit of the Startup Ecosystem. Tracking founders, momentum, and signals as they emerge.
Recruiting Runs on Relationships. The Tools Don't
Recruiting has been solving a relationship problem with search tools. After two years inside the system, Alexander Farr built Clera to fix it, reaching passive candidates through WhatsApp, iMessage, and email and already representing 80,000 people in relevant roles.
ScaleUp 10: Ones to Watch
OneEleven’s ScaleUp 10: Ones to Watch spotlighted Canadian scaleups building across AI, healthcare, manufacturing, mobility, and enterprise systems at DiscoveryX 2026. The cohort reflected where commercial traction and operational scale are emerging across Canada’s tech ecosystem.
Half of GI Cancer Patients Run Out of Options
When chemotherapy fails, immunotherapy does not respond, and targeted therapies do not apply, patients are left without a path forward. BiPER Therapeutics is developing an oral drug, selected by blood test, to treat that gap directly.